Endocrine Abstracts

Case history: A 65 year-old Caucasian gentleman was admitted with out-of-hospital VF arrest at work place. ROSC was achieved after shock by paramedics but developed multiple in-hospital arrests requiring (>100 shocks in 24 h) with incessant polymorphic ventricular tachycardia which was resistant to anti-arrhythmic therapy including drugs and pacing. Investigations revealed hypercalcemia and newly diagnosed high PTH with no change in mild LV dysfunction from previous myocardial...

40year old bodybuilder was re-referred to clinic with low mood, reduced libido, poor morning erections and fatigue. His past medical history included hypogonadal hypogonadism secondary to anabolic androgen abuse, mental health disease and personality disorders. He had undergone breast reconstruction surgery for bilateral gynaecomastia secondary to anabolic steroid use despite taking precautionary tamoxifen injections as per peer groups’ advice. Previously, he was lost for...

Introduction: Diabetes striatopathy (DS) is an extremely rare hyperglycaemic complication of diabetes with a prevalence reported as 1 in 100,0001. Though DS is commonly associated with a non-ketotic hyperglycaemic hyperosmolar state (HHS), it is occasionally reported in diabetic ketoacidosis (DKA). DS is known as non-ketotic hemichorea-hemiballismus due to its presentation with hyperkinetic movements but rarely presents as stroke-mimic2. Here we present a...

Introduction: Endocrine late effects can manifest in hemopoietic stem cell transplantation survivors who were exposed to myelosuppressive conditioning treatment. These include dysfunction of the hypothalamic/pituitary, thyroid, and gonads leading to premature ovarian insufficiency and primary amenorrhoea. In addition, metabolic dysregulation and increased risk of diabetes have been observed in these patients. The investigation for primary amenorrhoea in this condition can rare...

Cyclic Cushing’s syndrome (CCS) is a rare condition that involves recurring episodes of hypercortisolaemia, alternating with normocortisolemia at intervals ranging from a few days to several years. To diagnose CCS, it is necessary to demonstrate three cortisol peaks and two troughs. CCS is mostly seen in females and can be Adrenocorticotropic hormone (ACTH)-dependent or independent2. The common causes of CCS are Cushing’s Disease (55% ), ectopic ACTH syndrome (26%), ...

Introduction: Glioblastoma, an aggressive intracranial tumour usually is a solitary lesion and not commonly located in the sella turcica. Panhypopituitarism due to multicentric glioblastoma can present with a challenging clinical picture masking or delaying the underlying diagnosis. Case presentation: 58 year old female presented with marked behavioural change, reduced appetite, nausea, polyuria & increased thirst over 4-6 weeks precipitating into an...